As a board-certified Endocrinologist and former pharmacist, Dr. Marina Johnson ONLY prescribes bioidential “PHARMACEUTICAL” hormones, not COMPOUNDED products. Dr. Marina Johnson is a UCLA/USC trained Endocrinologist who has been in private practice since 1986 and has always utilized transdermal pharmaceutical therapy products since the original research by Dr. Howard Judd at UCLA in the late 70’s.
Compounded bioidentical hormones became more popular after 2002 when the Women’s Health Initiative (WHI) reported increased heart disease, strokes, dementia and breast cancer from the use of Prempro, the most commonly prescribed HRT which is taken by mouth. Because compounded products are not dispensed with FDA “black-box” warning labels like pharmaceutical bioidentical products (as patches, gels and creams), women naturally assume compounded creams are safer.
All HRT carries risks, but numerous clinical studies of pharmaceutical bioidentical HRT, show fewer risks and better benefits with topical bioidentical HRT compared to oral synthetic estrogens. No major medical studies have ever been published with “compounded” products, only with “phamaceutical” bioidentical products.
Dr. Johnson explains, As a matter of course, I always measure a woman’s estradiol blood level with a highly sensitive laboratory test. Some women receiving compounded hormones show NO detectable estrogen. For the most effective, safest product, I advise women to choose ‘pharmaceutical’ bioidentical HRT. I have no financial conflicts of interest or ties to any pharmaceutical company. My only objective is determining the most effective, safest therapy for my patients.
Compounded products play an important role for patients with allergies to pharmaceutical ingredients; to provide medications that are no longer commercially available; and to enable physicians to develop novel products.